Trajectory modeling of endothelial-to-mesenchymal transition reveals galectin-3 as a mediator in pulmonary fibrosis

The endothelial-to-mesenchymal transition (EndMT) is an important source of fibrotic cells in idiopathic pulmonary fibrosis (IPF). However, how endothelial cells (ECs) are activated and how EndMT impact IPF remain largely elusive. Here, we use unsupervised pseudotemporal analysis to recognize the he...

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Detalles Bibliográficos
Autores principales: Jia, Wangyue, Wang, Zhaoyan, Gao, Ceshu, Wu, Jian, Wu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998015/
https://www.ncbi.nlm.nih.gov/pubmed/33771973
http://dx.doi.org/10.1038/s41419-021-03603-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998015/
https://www.ncbi.nlm.nih.gov/pubmed/33771973
http://dx.doi.org/10.1038/s41419-021-03603-0

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