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Trajectory modeling of endothelial-to-mesenchymal transition reveals galectin-3 as a mediator in pulmonary fibrosis
The endothelial-to-mesenchymal transition (EndMT) is an important source of fibrotic cells in idiopathic pulmonary fibrosis (IPF). However, how endothelial cells (ECs) are activated and how EndMT impact IPF remain largely elusive. Here, we use unsupervised pseudotemporal analysis to recognize the he...
Autores principales: | Jia, Wangyue, Wang, Zhaoyan, Gao, Ceshu, Wu, Jian, Wu, Qiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998015/ https://www.ncbi.nlm.nih.gov/pubmed/33771973 http://dx.doi.org/10.1038/s41419-021-03603-0 |
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