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Pten is a key intrinsic factor regulating raphe 5-HT neuronal plasticity and depressive behaviors in mice

Serotonin (5-HT)-based antidepressants, selective serotonin reuptake inhibitors (SSRIs) aim to enhance serotonergic activity by blocking its reuptake. We propose PTEN as a target for an alternative approach for regulating 5-HT neuron activity in the brain and depressive behaviors. We show that PTEN...

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Detalles Bibliográficos
Autores principales: Chen, Ling, Gong, Wan-Kun, Yang, Cui-ping, Shao, Chan-Chan, Song, Ning-Ning, Chen, Jia-Yin, Zhou, Li-Qiang, Zhang, Kun-Shan, Li, Siguang, Huang, Zhili, Richter-Levin, Gal, Xu, Lin, Ding, Yu-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998026/
https://www.ncbi.nlm.nih.gov/pubmed/33771970
http://dx.doi.org/10.1038/s41398-021-01303-z