CRISPR/Cas9-Mediated Genome Editing in Comfrey (Symphytum officinale) Hairy Roots Results in the Complete Eradication of Pyrrolizidine Alkaloids

Comfrey (Symphytum officinale) is a medicinal plant with anti-inflammatory, analgesic, and proliferative properties. However, its pharmaceutical application is hampered by the co-occurrence of toxic pyrrolizidine alkaloids (PAs) in its tissues. Using a CRISPR/Cas9-based approach, we introduced detri...

Descripción completa

Detalles Bibliográficos
Autores principales: Zakaria, Mahmoud M., Schemmerling, Brigitte, Ober, Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998174/
https://www.ncbi.nlm.nih.gov/pubmed/33801907
http://dx.doi.org/10.3390/molecules26061498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998174/
https://www.ncbi.nlm.nih.gov/pubmed/33801907
http://dx.doi.org/10.3390/molecules26061498

Ejemplares similares