Generation and Evaluation of Isogenic iPSC as a Source of Cell Replacement Therapies in Patients with Kearns Sayre Syndrome

Kearns Sayre syndrome (KSS) is mitochondrial multisystem disorder with no proven effective treatment. The underlying cause for multisystem involvement is the energy deficit resulting from the load of mutant mitochondrial DNA (mtDNA), which manifests as loss of cells and tissue dysfunction. Therefore...

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Detalles Bibliográficos
Autores principales: Lester Sequiera, Glen, Srivastava, Abhay, Alagarsamy, Keshav Narayan, Rockman-Greenberg, Cheryl, Dhingra, Sanjiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998189/
https://www.ncbi.nlm.nih.gov/pubmed/33807701
http://dx.doi.org/10.3390/cells10030568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998189/
https://www.ncbi.nlm.nih.gov/pubmed/33807701
http://dx.doi.org/10.3390/cells10030568

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