Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart

Cardiac fibrosis is associated with most forms of cardiovascular disease. No reliable therapies targeting cardiac fibrosis are available, thus identifying novel drugs that can resolve or prevent fibrosis is needed. Tilorone, an antiviral agent, can prevent fibrosis in a mouse model of lung disease....

Descripción completa

Detalles Bibliográficos
Autores principales: Horlock, Duncan, Kaye, David M., Winbanks, Catherine E., Gao, Xiao-Ming, Kiriazis, Helen, Donner, Daniel G., Gregorevic, Paul, McMullen, Julie R., Bernardo, Bianca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998193/
https://www.ncbi.nlm.nih.gov/pubmed/33804032
http://dx.doi.org/10.3390/ph14030263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998193/
https://www.ncbi.nlm.nih.gov/pubmed/33804032
http://dx.doi.org/10.3390/ph14030263

Ejemplares similares