The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington’s Disease

Huntington’s disease (HD) is a monogenetic neurodegenerative disorder characterized by the accumulation of polyglutamine-expanded huntingtin (mHTT). There is currently no cure, and therefore disease-slowing remedies are sought to alleviate symptoms of the multifaceted disorder. Encouraging findings...

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Detalles Bibliográficos
Autores principales: Singer, Elisabeth, Hunanyan, Lilit, Melkonyan, Magda M., Weber, Jonasz J., Danielyan, Lusine, Nguyen, Huu Phuc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998230/
https://www.ncbi.nlm.nih.gov/pubmed/33809220
http://dx.doi.org/10.3390/ph14030257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998230/
https://www.ncbi.nlm.nih.gov/pubmed/33809220
http://dx.doi.org/10.3390/ph14030257

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