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Development of a Novel Weighted Ranking Method for Immunohistochemical Quantification of a Heterogeneously Expressed Protein in Gastro-Esophageal Cancers

SIMPLE SUMMARY: High levels of the protein Junctional Adhesion Molecule-A (JAM-A) have been linked with aggressive disease in patients with several different cancers. However, its distribution is often non-uniform (heterogeneous) across tumors, and can be difficult to quantify. JAM-A has also been l...

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Detalles Bibliográficos
Autores principales: Richards, Cathy E., Sheehan, Katherine M., Kay, Elaine W., Hedner, Charlotta, Borg, David, Fay, Joanna, O’Grady, Anthony, Hill, Arnold D. K., Jirström, Karin, Hopkins, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998246/
https://www.ncbi.nlm.nih.gov/pubmed/33805812
http://dx.doi.org/10.3390/cancers13061286