Combining Everolimus and Ku0063794 Promotes Apoptosis of Hepatocellular Carcinoma Cells via Reduced Autophagy Resulting from Diminished Expression of miR-4790-3p

It is challenging to overcome the low response rate of everolimus in the treatment of patients with hepatocellular carcinoma (HCC). To overcome this challenge, we combined everolimus with Ku0063794, the inhibitor of mTORC1 and mTORC2, to achieve higher anticancer effects. However, the precise mechan...

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Detalles Bibliográficos
Autores principales: Choi, Ho Joong, Park, Jung Hyun, Kim, Ok-Hee, Kim, Kee-Hwan, Hong, Ha Eun, Seo, Haeyeon, Kim, Say-June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998287/
https://www.ncbi.nlm.nih.gov/pubmed/33799789
http://dx.doi.org/10.3390/ijms22062859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998287/
https://www.ncbi.nlm.nih.gov/pubmed/33799789
http://dx.doi.org/10.3390/ijms22062859

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