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Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges

Idiosyncratic drug-induced liver injury (IDILI) remains a significant problem for patients and drug development. The idiosyncratic nature of IDILI makes mechanistic studies difficult, and little is known of its pathogenesis for certain. Circumstantial evidence suggests that most, but not all, IDILI...

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Detalles Bibliográficos
Autores principales: Jee, Alison, Sernoskie, Samantha Christine, Uetrecht, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998339/
https://www.ncbi.nlm.nih.gov/pubmed/33799477
http://dx.doi.org/10.3390/ijms22062954