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Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity

Experimental evidence indicates that the activation of ionotropic glutamate receptors plays an important role in neurological disorders’ models such as epilepsy, cerebral ischemia and trauma. The glutamate receptor agonist kainic acid (KA) induces seizures and excitotoxic cell death in the CA3 regio...

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Detalles Bibliográficos
Autores principales: Landucci, Elisa, Mazzantini, Costanza, Buonvicino, Daniela, Pellegrini-Giampietro, Domenico E., Bergonzi, Maria Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998420/
https://www.ncbi.nlm.nih.gov/pubmed/33805696
http://dx.doi.org/10.3390/molecules26061592