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Neuroprotective Effects of Thymoquinone by the Modulation of ER Stress and Apoptotic Pathway in In Vitro Model of Excitotoxicity
Experimental evidence indicates that the activation of ionotropic glutamate receptors plays an important role in neurological disorders’ models such as epilepsy, cerebral ischemia and trauma. The glutamate receptor agonist kainic acid (KA) induces seizures and excitotoxic cell death in the CA3 regio...
Autores principales: | Landucci, Elisa, Mazzantini, Costanza, Buonvicino, Daniela, Pellegrini-Giampietro, Domenico E., Bergonzi, Maria Camilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998420/ https://www.ncbi.nlm.nih.gov/pubmed/33805696 http://dx.doi.org/10.3390/molecules26061592 |
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