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Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE

Pertussis toxin (PTX) is a required co-adjuvant for experimental autoimmune encephalomyelitis (EAE) induced by immunization with myelin antigen. However, PTX’s effects on EAE induced by the transfer of myelin-specific T helper cells is not known. Therefore, we investigated how PTX affects the Th17 t...

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Detalles Bibliográficos
Autores principales: Maria, Zahra, Turner, Emma, Agasing, Agnieshka, Kumar, Gaurav, Axtell, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998427/
https://www.ncbi.nlm.nih.gov/pubmed/33805762
http://dx.doi.org/10.3390/ijms22062924