Preclinical Evaluation of the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor, Ribociclib, and Cetuximab in Squamous Cell Carcinoma of the Head and Neck

SIMPLE SUMMARY: We previously showed that ribociclib induces cell cycle arrest in some human papillomavirus (HPV)-negative squamous cell carcinomas of the head and neck (SCCHN) models. However, in vivo, ribociclib has only a cytostatic effect, suggesting that its activity needs to be optimized in co...

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Detalles Bibliográficos
Autores principales: van Caloen, Gabrielle, Schmitz, Sandra, van Marcke, Cédric, Caignet, Xavier, Mendola, Antonella, Pyr dit Ruys, Sébastien, Roger, Pierre P., Vertommen, Didier, Machiels, Jean-Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998503/
https://www.ncbi.nlm.nih.gov/pubmed/33809148
http://dx.doi.org/10.3390/cancers13061251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998503/
https://www.ncbi.nlm.nih.gov/pubmed/33809148
http://dx.doi.org/10.3390/cancers13061251

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