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R-Spondin 2 and WNT/CTNNB1 Signaling Pathways Are Required for Porcine Follicle Development and In Vitro Maturation

SIMPLE SUMMARY: A recent mouse study reported that R-spondin2 promotes follicular development by activating WNT/Catenin beta-1 (CTNNB1) signaling in granulated cells. Our results demonstrate that RSPO2, CTNNB1, G-protein coupled receptor 4 (LGR4), and G-protein coupled receptor 5 (LGR5) factors play...

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Detalles Bibliográficos
Autores principales: Hwang, Seon-Ung, Yoon, Junchul David, Kim, Mirae, Cai, Lian, Choi, Hyerin, Oh, Dongjin, Kim, Eunhye, Hyun, Sang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998564/
https://www.ncbi.nlm.nih.gov/pubmed/33807916
http://dx.doi.org/10.3390/ani11030709