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DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients

SIMPLE SUMMARY: Functional aneuploidy as determined by expression of the 70 genes of the CIN70 score, influences prognosis. The importance of DNA repair protein expression and activity in this context is unclear. We can show here that a high CIN70 score is associated with increased expression of 44...

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Detalles Bibliográficos
Autores principales: Bold, Ioan T., Specht, Ann-Kathrin, Droste, Conrad F., Zielinski, Alexandra, Meyer, Felix, Clauditz, Till S., Münscher, Adrian, Werner, Stefan, Rothkamm, Kai, Petersen, Cordula, Borgmann, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998578/
https://www.ncbi.nlm.nih.gov/pubmed/33801877
http://dx.doi.org/10.3390/cancers13061194