Data-Driven Math Model of FLT3-ITD Acute Myeloid Leukemia Reveals Potential Therapeutic Targets

FLT3-mutant acute myeloid leukemia (AML) is an aggressive form of leukemia with poor prognosis. Treatment with FLT3 inhibitors frequently produces a clinical response, but the disease nevertheless often recurs. Recent studies have revealed system-wide gene expression changes in FLT3-mutant AML cell...

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Detalles Bibliográficos
Autores principales: Wooten, David J., Gebru, Melat, Wang, Hong-Gang, Albert, Réka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998618/
https://www.ncbi.nlm.nih.gov/pubmed/33799721
http://dx.doi.org/10.3390/jpm11030193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998618/
https://www.ncbi.nlm.nih.gov/pubmed/33799721
http://dx.doi.org/10.3390/jpm11030193

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