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Phloridzin Acts as an Inhibitor of Protein-Tyrosine Phosphatase MEG2 Relevant to Insulin Resistance

Inhibition of the megakaryocyte protein tyrosine phosphatase 2 (PTP-MEG2, also named PTPN9) activity has been shown to be a potential therapeutic strategy for the treatment of type 2 diabetes. Previously, we reported that PTP-MEG2 knockdown enhances adenosine monophosphate activated protein kinase (...

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Detalles Bibliográficos
Autores principales: Yoon, Sun-Young, Yu, Jae Sik, Hwang, Ji Young, So, Hae Min, Seo, Seung Oh, Kim, Jung Kyu, Jang, Tae Su, Chung, Sang J., Kim, Ki Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998658/
https://www.ncbi.nlm.nih.gov/pubmed/33799458
http://dx.doi.org/10.3390/molecules26061612