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Harnessing the IL-21-BATF Pathway in the CD8(+) T Cell Anti-Tumor Response

SIMPLE SUMMARY: In cancer, CD8(+) T cells enter a state of dysfunction within the tumor that prevents them from targeting and killing tumor cells. Our study aims to uncover how CD8(+) T cells can be helped by CD4(+) T cells or modified in order to improve their effector function against cancer. Thus...

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Detalles Bibliográficos
Autores principales: Topchyan, Paytsar, Xin, Gang, Chen, Yao, Zheng, Shikan, Burns, Robert, Shen, Jian, Kasmani, Moujtaba Y., Kudek, Matthew, Yang, Na, Cui, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998696/
https://www.ncbi.nlm.nih.gov/pubmed/33809259
http://dx.doi.org/10.3390/cancers13061263