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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives

The genome of the human intracellular pathogen Mycobacterium tuberculosis encodes an unusually large number of epoxide hydrolases, which are thought to be involved in lipid metabolism and detoxification reactions needed to endure the hostile environment of host macrophages. These enzymes therefore r...

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Detalles Bibliográficos
Autores principales: Madacki, Jan, Kopál, Martin, Jackson, Mary, Korduláková, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998700/
https://www.ncbi.nlm.nih.gov/pubmed/33809178
http://dx.doi.org/10.3390/ijms22062884