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Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives
The genome of the human intracellular pathogen Mycobacterium tuberculosis encodes an unusually large number of epoxide hydrolases, which are thought to be involved in lipid metabolism and detoxification reactions needed to endure the hostile environment of host macrophages. These enzymes therefore r...
Autores principales: | Madacki, Jan, Kopál, Martin, Jackson, Mary, Korduláková, Jana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998700/ https://www.ncbi.nlm.nih.gov/pubmed/33809178 http://dx.doi.org/10.3390/ijms22062884 |
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