Dose-Dependent Solubility–Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

We investigated the solubility–permeability interplay using a solubilizer additive under non-sink conditions. Sodium lauryl sulfate (SLS) was used as a solubilizer additive. The solubility and permeability of two poorly soluble drugs at various doses, with or without SLS, were evaluated by flux meas...

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Detalles Bibliográficos
Autores principales: Sugita, Kazuya, Takata, Noriyuki, Yonemochi, Etsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998705/
https://www.ncbi.nlm.nih.gov/pubmed/33801447
http://dx.doi.org/10.3390/pharmaceutics13030323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998705/
https://www.ncbi.nlm.nih.gov/pubmed/33801447
http://dx.doi.org/10.3390/pharmaceutics13030323

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