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Dose-Dependent Solubility–Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

We investigated the solubility–permeability interplay using a solubilizer additive under non-sink conditions. Sodium lauryl sulfate (SLS) was used as a solubilizer additive. The solubility and permeability of two poorly soluble drugs at various doses, with or without SLS, were evaluated by flux meas...

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Detalles Bibliográficos
Autores principales:	Sugita, Kazuya, Takata, Noriyuki, Yonemochi, Etsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998705/ https://www.ncbi.nlm.nih.gov/pubmed/33801447 http://dx.doi.org/10.3390/pharmaceutics13030323

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