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TAM Receptor Inhibition–Implications for Cancer and the Immune System

SIMPLE SUMMARY: TAM receptors are a family of receptor tyrosine kinases, comprising Tyro3, Axl and MerTK. Their primary role is in digestion of dying cells by macrophages without alarming the immune system. TAM receptors are also expressed by cancer cells in which signaling is oncogenic, and for thi...

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Detalles Bibliográficos
Autores principales: Aehnlich, Pia, Powell, Richard Morgan, Peeters, Marlies J. W., Rahbech, Anne, thor Straten, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998716/
https://www.ncbi.nlm.nih.gov/pubmed/33801886
http://dx.doi.org/10.3390/cancers13061195