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The Phenoxyphenol Compound diTFPP Mediates Exogenous C(2)-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is a severe disease that accounts for 80% of liver cancers. Chemotherapy is the primary therapeutic strategy for patients who cannot be treated with surgery or who have late-stage HCC. C(2)-ceramide is an effective reagent that has been found to inhibit the growth of m...

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Detalles Bibliográficos
Autores principales: Chang, Wen-Tsan, Bow, Yung-Ding, Chen, Yen-Chun, Li, Chia-Yang, Chen, Jeff Yi-Fu, Chu, Yi-Ching, Teng, Yen-Ni, Li, Ruei-Nian, Chiu, Chien-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998835/
https://www.ncbi.nlm.nih.gov/pubmed/33807856
http://dx.doi.org/10.3390/antiox10030394