NFκB-Activated COX2/PGE(2)/EP4 Axis Controls the Magnitude and Selectivity of BCG-Induced Inflammation in Human Bladder Cancer Tissues

SIMPLE SUMMARY: The clinical effectiveness of Bacillus Calmette-Guérin (BCG) is limited to patients with early stages of bladder cancer (BlCa) and its effects are often transient. To understand the mechanisms limiting the effectiveness of BCG, we evaluated its impact on the human BlCa tumor microenv...

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Detalles Bibliográficos
Autores principales: Ibrahim, Omar M., Basse, Per H., Jiang, Weijian, Guru, Khurshid, Chatta, Gurkamal, Kalinski, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998891/
https://www.ncbi.nlm.nih.gov/pubmed/33809455
http://dx.doi.org/10.3390/cancers13061323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998891/
https://www.ncbi.nlm.nih.gov/pubmed/33809455
http://dx.doi.org/10.3390/cancers13061323

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