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Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis

Systemic light-chain (AL) amyloidosis is caused by a small B cell, most commonly a plasma cell (PC), clone that produces toxic light chains (LC) that cause organ dysfunction and deposits in tissues. Due to the production of amyloidogenic, misfolded LC, AL PCs display peculiar biologic features. The...

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Detalles Bibliográficos
Autores principales: Palladini, Giovanni, Milani, Paolo, Malavasi, Fabio, Merlini, Giampaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998921/
https://www.ncbi.nlm.nih.gov/pubmed/33806310
http://dx.doi.org/10.3390/cells10030545