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Daratumumab in the Treatment of Light-Chain (AL) Amyloidosis
Systemic light-chain (AL) amyloidosis is caused by a small B cell, most commonly a plasma cell (PC), clone that produces toxic light chains (LC) that cause organ dysfunction and deposits in tissues. Due to the production of amyloidogenic, misfolded LC, AL PCs display peculiar biologic features. The...
Autores principales: | Palladini, Giovanni, Milani, Paolo, Malavasi, Fabio, Merlini, Giampaolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998921/ https://www.ncbi.nlm.nih.gov/pubmed/33806310 http://dx.doi.org/10.3390/cells10030545 |
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