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Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity

Although epoxyeicosatrienoic acid (EET) analogs have performed well in several acute and chronic kidney disease models, targeted delivery of EET analogs to the kidney can be reasonably expected to reduce the level of drug needed to achieve a therapeutic effect and obviate possible side effects. For...

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Detalles Bibliográficos
Autores principales: Imig, John D., Hye Khan, Md Abdul, Burkhan, Anna, Chen, Guan, Adebesin, Adeniyi Michael, Falck, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998941/
https://www.ncbi.nlm.nih.gov/pubmed/33801911
http://dx.doi.org/10.3390/ijms22062793