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Synthesis and Characterization of Bone Binding Antibiotic-1 (BBA-1), a Novel Antimicrobial for Orthopedic Applications

Osteomyelitis and orthopedic infections are major clinical problems, limited by a lack of antibiotics specialized for such applications. In this paper, we describe the design and synthesis of a novel bone-binding antibiotic (BBA-1) and its subsequent structural and functional characterization. The s...

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Detalles Bibliográficos
Autores principales: Kamble, Sumedh, Valtchev, Peter, Dao, Aiken, Pelras, Théophile, Rogers, Michael J, Savage, Paul B., Dehghani, Fariba, Schindeler, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999004/
https://www.ncbi.nlm.nih.gov/pubmed/33799713
http://dx.doi.org/10.3390/molecules26061541