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Chromatin-Spliceosome Mutations in Acute Myeloid Leukemia

SIMPLE SUMMARY: Recent genomic studies have identified chromatin-spliceosome (CS)-acute myeloid leukemia (AML) as a new subgroup of AML. CS-AML is defined by several mutations that perturb epigenetic regulation, such as those affecting splicing factors, cohesin components, transcription factors, and...

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Detalles Bibliográficos
Autores principales: Ochi, Yotaro, Ogawa, Seishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999050/
https://www.ncbi.nlm.nih.gov/pubmed/33799787
http://dx.doi.org/10.3390/cancers13061232