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Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage

SIMPLE SUMMARY: Endocrine therapy with tamoxifen or other endocrine drugs represents the standard treatment for estrogen receptor-positive breast cancer. In spite of effectiveness of this therapy, onset of drug resistance worsens the prognosis of about 30% of patients. Autophagy has recently been pr...

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Detalles Bibliográficos
Autores principales: Actis, Chiara, Muzio, Giuliana, Autelli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999102/
https://www.ncbi.nlm.nih.gov/pubmed/33809171
http://dx.doi.org/10.3390/cancers13061252