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Autophagy Triggers Tamoxifen Resistance in Human Breast Cancer Cells by Preventing Drug-Induced Lysosomal Damage
SIMPLE SUMMARY: Endocrine therapy with tamoxifen or other endocrine drugs represents the standard treatment for estrogen receptor-positive breast cancer. In spite of effectiveness of this therapy, onset of drug resistance worsens the prognosis of about 30% of patients. Autophagy has recently been pr...
Autores principales: | Actis, Chiara, Muzio, Giuliana, Autelli, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999102/ https://www.ncbi.nlm.nih.gov/pubmed/33809171 http://dx.doi.org/10.3390/cancers13061252 |
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