Macrophage Plasticity and Function in the Lung Tumour Microenvironment Revealed in 3D Heterotypic Spheroid and Explant Models

In non-small cell lung cancer (NSCLC), stroma-resident and tumour-infiltrating macrophages may facilitate an immunosuppressive tumour microenvironment (TME) and hamper immunotherapeutic responses. Analysis of tumour-associated macrophage (TAM) plasticity in NSCLC is largely lacking. We established a...

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Detalles Bibliográficos
Autores principales: Evans, Lauren, Milward, Kate, Attanoos, Richard, Clayton, Aled, Errington, Rachel, Tabi, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999110/
https://www.ncbi.nlm.nih.gov/pubmed/33804204
http://dx.doi.org/10.3390/biomedicines9030302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999110/
https://www.ncbi.nlm.nih.gov/pubmed/33804204
http://dx.doi.org/10.3390/biomedicines9030302

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