Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants

Because studies of rare variant effects on gene expression have limited power, we investigated set-based methods to identify rare expression quantitative trait loci (eQTL) related to Alzheimer disease (AD). Gene-level and pathway-level cis rare-eQTL mapping was performed genome-wide using gene expre...

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Detalles Bibliográficos
Autores principales: Patel, Devanshi, Zhang, Xiaoling, Farrell, John J., Lunetta, Kathryn L., Farrer, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999141/
https://www.ncbi.nlm.nih.gov/pubmed/33804025
http://dx.doi.org/10.3390/genes12030419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999141/
https://www.ncbi.nlm.nih.gov/pubmed/33804025
http://dx.doi.org/10.3390/genes12030419

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