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Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca(2+)

Mitochondrial autophagy (or mitophagy) is essential for mitochondrial quality control, which is critical for cellular and organismal health by attenuating reactive oxygen species generation and maintaining bioenergy homeostasis. Previously, we showed that mitophagy is activated in human cells throug...

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Detalles Bibliográficos
Autores principales: Song, Seon Beom, Park, Jin Sung, Jang, So Young, Hwang, Eun Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999186/
https://www.ncbi.nlm.nih.gov/pubmed/33802063
http://dx.doi.org/10.3390/cells10030612