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Distinct properties and functions of CTCF revealed by a rapidly inducible degron system

CCCTC-binding factor (CTCF) is a conserved zinc finger transcription factor implicated in a wide range of functions, including genome organization, transcription activation, and elongation. To explore the basis for CTCF functional diversity, we coupled an auxin-induced degron system with precision n...

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Detalles Bibliográficos
Autores principales: Luan, Jing, Xiang, Guanjue, Gómez-García, Pablo Aurelio, Tome, Jacob M., Zhang, Zhe, Vermunt, Marit W., Zhang, Haoyue, Huang, Anran, Keller, Cheryl A., Giardine, Belinda M., Zhang, Yu, Lan, Yemin, Lis, John T., Lakadamyali, Melike, Hardison, Ross C., Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999233/
https://www.ncbi.nlm.nih.gov/pubmed/33626344
http://dx.doi.org/10.1016/j.celrep.2021.108783