Cargando…
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
CCCTC-binding factor (CTCF) is a conserved zinc finger transcription factor implicated in a wide range of functions, including genome organization, transcription activation, and elongation. To explore the basis for CTCF functional diversity, we coupled an auxin-induced degron system with precision n...
Autores principales: | Luan, Jing, Xiang, Guanjue, Gómez-García, Pablo Aurelio, Tome, Jacob M., Zhang, Zhe, Vermunt, Marit W., Zhang, Haoyue, Huang, Anran, Keller, Cheryl A., Giardine, Belinda M., Zhang, Yu, Lan, Yemin, Lis, John T., Lakadamyali, Melike, Hardison, Ross C., Blobel, Gerd A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999233/ https://www.ncbi.nlm.nih.gov/pubmed/33626344 http://dx.doi.org/10.1016/j.celrep.2021.108783 |
Ejemplares similares
-
CTCF and transcription influence chromatin structure re-configuration after mitosis
por: Zhang, Haoyue, et al.
Publicado: (2021) -
S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data
por: Xiang, Guanjue, et al.
Publicado: (2020) -
CLIMB: High-dimensional association detection in large scale genomic data
por: Koch, Hillary, et al.
Publicado: (2022) -
S3V2-IDEAS: a package for normalizing, denoising and integrating epigenomic datasets across different cell types
por: Xiang, Guanjue, et al.
Publicado: (2021) -
Chromatin Structure Dynamics During the Mitosis to G1-Phase Transition
por: Zhang, Haoyue, et al.
Publicado: (2019)