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Hypoxia-Induced Reactivity of Tumor-Associated Astrocytes Affects Glioma Cell Properties

Glioblastoma is characterized by extensive necrotic areas with surrounding hypoxia. The cancer cell response to hypoxia in these areas is well-described; it involves a metabolic shift and an increase in stem cell-like characteristics. Less is known about the hypoxic response of tumor-associated astr...

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Detalles Bibliográficos
Autores principales: Pantazopoulou, Vasiliki, Jeannot, Pauline, Rosberg, Rebecca, Berg, Tracy J., Pietras, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999295/
https://www.ncbi.nlm.nih.gov/pubmed/33802060
http://dx.doi.org/10.3390/cells10030613