Iron Availability in Tissue Microenvironment: The Key Role of Ferroportin

Body iron levels are regulated by hepcidin, a liver-derived peptide that exerts its function by controlling the presence of ferroportin (FPN), the sole cellular iron exporter, on the cell surface. Hepcidin binding leads to FPN internalization and degradation, thereby inhibiting iron release, in part...

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Detalles Bibliográficos
Autores principales: Gammella, Elena, Correnti, Margherita, Cairo, Gaetano, Recalcati, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999357/
https://www.ncbi.nlm.nih.gov/pubmed/33804198
http://dx.doi.org/10.3390/ijms22062986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999357/
https://www.ncbi.nlm.nih.gov/pubmed/33804198
http://dx.doi.org/10.3390/ijms22062986

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