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Plasminogen Activator Inhibitor-1 Secretion by Autophagy Contributes to Melanoma Resistance to Chemotherapy through Tumor Microenvironment Modulation

SIMPLE SUMMARY: Dysregulation of tumor autophagy is implicated in cancer progression and chemotherapeutic response. It is unclear how tumor autophagy modulates tumor microenvironment and thereby contributes to chemoresistance. In this study, we found that autophagy-dependent plasminogen activator in...

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Detalles Bibliográficos
Autores principales: Tzeng, Hong-Tai, Yang, Jenq-Lin, Tseng, Yu-Ju, Lee, Chih-Hung, Chen, Wei-Ju, Chyuan, I-Tsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999393/
https://www.ncbi.nlm.nih.gov/pubmed/33809137
http://dx.doi.org/10.3390/cancers13061253