Disulfiram Acts as a Potent Radio-Chemo Sensitizer in Head and Neck Squamous Cell Carcinoma Cell Lines and Transplanted Xenografts

The poor prognosis of locally advanced and metastatic head and neck squamous cell carcinoma (HNSCC) is primarily mediated by the functional properties of cancer stem cells (CSCs) and resistance to chemoradiotherapy. We investigated whether the aldehyde dehydrogenase (ALDH) inhibitor disulfiram (DSF)...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Wenhao, Qian, Xu, Ochsenreither, Sebastian, Soldano, Ferrone, DeLeo, Albert B., Sudhoff, Holger, Oppel, Felix, Kuppig, Andreas, Klinghammer, Konrad, Kaufmann, Andreas M., Albers, Andreas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999545/
https://www.ncbi.nlm.nih.gov/pubmed/33671083
http://dx.doi.org/10.3390/cells10030517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999545/
https://www.ncbi.nlm.nih.gov/pubmed/33671083
http://dx.doi.org/10.3390/cells10030517

Ejemplares similares