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Characterization and Vector Competence Studies of Chikungunya Virus Lacking Repetitive Motifs in the 3′ Untranslated Region of the Genome

Using reverse genetics, we analyzed a chikungunya virus (CHIKV) isolate of the Indian Ocean lineage lacking direct repeat (DR) elements in the 3′ untranslated region, namely DR1a and DR2a. While this deletion mutant CHIKV-∆DR exhibited growth characteristics comparable to the wild-type virus in Baby...

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Detalles Bibliográficos
Autores principales: Karliuk, Yauhen, vom Hemdt, Anja, Wieseler, Janett, Pfeffer, Martin, Kümmerer, Beate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999577/
https://www.ncbi.nlm.nih.gov/pubmed/33806267
http://dx.doi.org/10.3390/v13030403