Characterization of P-Glycoprotein Inhibitors for Evaluating the Effect of P-Glycoprotein on the Intestinal Absorption of Drugs

For developing oral drugs, it is necessary to predict the oral absorption of new chemical entities accurately. However, it is difficult because of the involvement of efflux transporters, including P-glycoprotein (P-gp), in their absorption process. In this study, we conducted a comparative analysis...

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Detalles Bibliográficos
Autores principales: Kono, Yusuke, Kawahara, Iichiro, Shinozaki, Kohei, Nomura, Ikuo, Marutani, Honoka, Yamamoto, Akira, Fujita, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999658/
https://www.ncbi.nlm.nih.gov/pubmed/33804018
http://dx.doi.org/10.3390/pharmaceutics13030388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999658/
https://www.ncbi.nlm.nih.gov/pubmed/33804018
http://dx.doi.org/10.3390/pharmaceutics13030388

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