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Simultaneous CD8(+) T-Cell Immune Response against SARS-Cov-2 S, M, and N Induced by Endogenously Engineered Extracellular Vesicles in Both Spleen and Lungs

Most advanced vaccines against severe acute respiratory syndrome coronavirus (SARS-CoV)-2 are designed to induce antibodies against spike (S) protein. Differently, we developed an original strategy to induce CD8(+) T cytotoxic lymphocyte (CTL) immunity based on in vivo engineering of extracellular v...

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Detalles Bibliográficos
Autores principales: Ferrantelli, Flavia, Chiozzini, Chiara, Manfredi, Francesco, Giovannelli, Andrea, Leone, Patrizia, Federico, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999804/
https://www.ncbi.nlm.nih.gov/pubmed/33801926
http://dx.doi.org/10.3390/vaccines9030240