Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

SIMPLE SUMMARY: The use of BRD4 inhibitors has emerged as a novel therapeutic approach in a wide variety of tumors including the triple negative breast cancer. Moreover, PP2A has been proposed as the phosphatase involved in regulating BRD4 phosphorylation and stabilization. Our aim was to evaluate f...

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Detalles Bibliográficos
Autores principales: Sanz-Álvarez, Marta, Cristóbal, Ion, Luque, Melani, Santos, Andrea, Zazo, Sandra, Madoz-Gúrpide, Juan, Caramés, Cristina, Chiang, Cheng-Ming, García-Foncillas, Jesús, Eroles, Pilar, Albanell, Joan, Rojo, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999847/
https://www.ncbi.nlm.nih.gov/pubmed/33809005
http://dx.doi.org/10.3390/cancers13061246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999847/
https://www.ncbi.nlm.nih.gov/pubmed/33809005
http://dx.doi.org/10.3390/cancers13061246

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