Obeticholic Acid Inhibits Anxiety via Alleviating Gut Microbiota-Mediated Microglia Accumulation in the Brain of High-Fat High-Sugar Diet Mice

Anxiety is one of the complications of metabolic disorders (MDs). Obeticholic acid (OCA), the bile acids (BAs) derivative, is a promising agent for improving MDs in association with gut dysbiosis. Yet, its protective effect on MDs-driven anxiety remains unknown. Here, we assessed the serum biochemic...

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Detalles Bibliográficos
Autores principales: Wu, Li, Han, Yuqiu, Zheng, Zhipeng, Zhu, Shuai, Chen, Jun, Yao, Yuanyuan, Yue, Siqing, Teufel, Andreas, Weng, Honglei, Li, Lanjuan, Wang, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999854/
https://www.ncbi.nlm.nih.gov/pubmed/33803974
http://dx.doi.org/10.3390/nu13030940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999854/
https://www.ncbi.nlm.nih.gov/pubmed/33803974
http://dx.doi.org/10.3390/nu13030940

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