Lumacaftor and Matrine: Possible Therapeutic Combination to Counteract the Inflammatory Process in Cystic Fibrosis

Cystic fibrosis is a monogenic, autosomal, recessive disease characterized by an alteration of chloride transport caused by mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene. The loss of Phe residue in position 508 (ΔF508-CFTR) causes an incorrect folding of the protei...

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Detalles Bibliográficos
Autores principales: Pecoraro, Michela, Franceschelli, Silvia, Pascale, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999856/
https://www.ncbi.nlm.nih.gov/pubmed/33805605
http://dx.doi.org/10.3390/biom11030422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999856/
https://www.ncbi.nlm.nih.gov/pubmed/33805605
http://dx.doi.org/10.3390/biom11030422

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