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Nucleoredoxin Knockdown in SH-SY5Y Cells Promotes Cell Renewal

Nucleoredoxin (NXN) is a redox regulator of Disheveled and thereby of WNT signaling. Deficiency in mice leads to cranial dysmorphisms and defects of heart, brain, and bone, suggesting defects of cell fate determination. We used shRNA-mediated knockdown of NXN in SH-SY5Y neuroblastoma cells to study...

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Detalles Bibliográficos
Autores principales: Valek, Lucie, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999887/
https://www.ncbi.nlm.nih.gov/pubmed/33805811
http://dx.doi.org/10.3390/antiox10030449