The Uncovered Function of the Drosophila GBA1a-Encoded Protein

Human GBA1 encodes lysosomal acid β-glucocerebrosidase (GCase), which hydrolyzes cleavage of the beta-glucosidic linkage of glucosylceramide (GlcCer). Mutations in this gene lead to reduced GCase activity, accumulation of glucosylceramide and glucosylsphingosine, and development of Gaucher disease (...

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Detalles Bibliográficos
Autores principales: Cabasso, Or, Paul, Sumit, Maor, Gali, Pasmanik-Chor, Metsada, Kallemeijn, Wouter, Aerts, Johannes, Horowitz, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000066/
https://www.ncbi.nlm.nih.gov/pubmed/33809074
http://dx.doi.org/10.3390/cells10030630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8000066/
https://www.ncbi.nlm.nih.gov/pubmed/33809074
http://dx.doi.org/10.3390/cells10030630

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